Entry Detail


General Information

Database ID:exR0510847
RNA Name:ACER3
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):76860867End Site(bp):77026797
External Links:ENSG00000078124



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SLC39A13
chr11
47407132
47416496
+
HLA-A
chr6
29941260
29945884
+
BANP
chr16
87949244
88077318
+
ARCN1
chr11
118572390
118603033
+
PPIB
chr15
64155812
64163205
-
NDUFC2-KCTD14
chr11
78016971
78079865
-
CCT2
chr12
69585426
69601570
+
PTRH2
chr17
59674636
59707626
-
TBC1D4
chr13
75283503
75482169
-
NDUFC2
chr11
78068297
78079862
-
KLHL7
chr7
23105758
23177914
+
EIF3C
chr16
28688558
28735730
+
DNAJB6
chr7
157335381
157417439
+
RPS10-NUDT3
chr6
34284887
34426071
-
RPS10
chr6
34417454
34426069
-
C22orf39
chr22
19351368
19448232
-
MRFAP1L1
chr4
6707701
6709865
-
SLC3A2
chr11
62856102
62888875
+
TSKU
chr11
76782251
76798153
+
DPH1
chr17
2030110
2043430
+
SYAP1
chrX
16719612
16765340
+
HNRNPH1
chr5
179614178
179634784
-
SHMT2
chr12
57229573
57234935
+
RPL27A
chr11
8682788
8714759
+
FAM3C
chr7
121348878
121396364
-
PRDX3
chr10
119167720
119178812
-
CNN2
chr19
1026586
1039068
+
NOTCH2
chr1
119911553
120100779
-
CDC42SE2
chr5
131245493
131398447
+
AC010422.3
chr19
12643831
12648397
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-27a-3p
chr19
13836447
13836467
-
hsa-miR-129-5p
chr7
128207876
128207896
+
hsa-miR-27b-3p
chr9
95085505
95085525
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.