Entry Detail


General Information

Database ID:exR0510848
RNA Name:ACHE
RNA Type:mRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):100889994End Site(bp):100896974
External Links:ENSG00000087085



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CPNE2
chr16
57092583
57148369
+
GNAI2
chr3
50226292
50259362
+
GOLGA7
chr8
41490396
41510980
+
GORASP1
chr3
39096659
39108363
-
HLA-A
chr6
29941260
29945884
+
PCDHGA1
chr5
141330571
141512981
+
PCDHGA10
chr5
141412987
141512979
+
PCDHGA11
chr5
141421047
141512975
+
PCDHGA12
chr5
141430507
141512975
+
PCDHGA2
chr5
141338760
141512975
+
PCDHGA3
chr5
141343829
141512979
+
PCDHGA4
chr5
141355021
141512975
+
PCDHGA5
chr5
141364232
141512979
+
PCDHGA6
chr5
141373914
141512979
+
PCDHGA7
chr5
141382739
141512975
+
PCDHGA8
chr5
141390157
141512979
+
PCDHGA9
chr5
141402932
141512979
+
PCDHGB1
chr5
141350102
141512979
+
PCDHGB2
chr5
141360042
141512979
+
PCDHGB3
chr5
141370242
141512975
+
PCDHGB4
chr5
141387698
141512979
+
PCDHGB5
chr5
141397987
141512979
+
PCDHGB6
chr5
141408021
141512979
+
PCDHGB7
chr5
141417645
141512979
+
PCDHGC3
chr5
141475947
141512977
+
PCDHGC4
chr5
141484997
141512979
+
PCDHGC5
chr5
141489121
141512979
+
PLD3
chr19
40348456
40380439
+
UBQLN1
chr9
83659968
83707958
-
UQCRHL
chr1
15807169
15809348
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.