Entry Detail


General Information

Database ID:exR0510849
RNA Name:ACIN1
RNA Type:mRNA
Chromosome:chr14
Starnd:-
Coordinate:
Start Site(bp):23058564End Site(bp):23095614
External Links:ENSG00000100813



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HNRNPA2B1
chr7
26173057
26201529
-
CD74
chr5
150400041
150412929
-
EEF1G
chr11
62559596
62574086
-
MANEAL
chr1
37793802
37801137
+
CGN
chr1
151510510
151538692
+
LRRC58
chr3
120324509
120349354
-
RGPD5
chr2
109792758
109857705
+
IVNS1ABP
chr1
185296388
185317273
-
TTLL3
chr3
9808086
9855138
+
SDHAF3
chr7
97117698
97181763
+
JAGN1
chr3
9890574
9894349
+
RPL39
chrX
119786504
119791630
-
CFAP20
chr16
58113592
58129381
-
PCDHGA3
chr5
141343829
141512979
+
PCDHGA1
chr5
141330571
141512981
+
ALDH7A1
chr5
126531200
126595362
-
EEF1A1
chr6
73515750
73523797
-
PMF1
chr1
156212993
156240042
+
WWC3
chrX
10015562
10144478
+
RACK1
chr5
181236897
181248096
-
SFXN1
chr5
175477062
175529742
+
TPT1
chr13
45333471
45341370
-
MRPS7
chr17
75261674
75266376
+
RNASEK
chr17
7012417
7014532
+
TRAF7
chr16
2155698
2178129
+
CERK
chr22
46684410
46738252
-
TSC2
chr16
2047967
2089491
+
CNP
chr17
41966763
41977740
+
RPL11
chr1
23691742
23696835
+
PCDHGA10
chr5
141412987
141512979
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC027682.2
chr16
67542123
67542963
-
AC124068.2
chr15
89335053
89336161
+
AL132780.1
chr14
22929607
22956374
+
AL355075.4
chr14
20343048
20343685
-
AP001496.2
chr18
5232876
5238526
-
AP005263.1
chr18
9102736
9254346
+
BISPR
chr19
17405686
17419324
+
NEAT1
chr11
65422774
65445540
+
XIST
chrX
73820649
73852723
-
Z83843.1
chrX
74209976
74213660
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.