Entry Detail


General Information

Database ID:exR0510857
RNA Name:ACOT2
RNA Type:mRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):73567620End Site(bp):73575658
External Links:ENSG00000119673



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACOT1
chr14
73537143
73543796
+
ACOT4
chr14
73591706
73596496
+
ACOT6
chr14
73610945
73619888
+
ACSL4
chrX
109624244
109733403
-
AL136295.5
chr14
24147548
24166452
+
ANKRD16
chr10
5861616
5889906
-
CRABP2
chr1
156699606
156705816
-
ESYT2
chr7
158730995
158830253
-
GOT2
chr16
58707131
58734342
-
LIN28A
chr1
26410817
26429728
+
MRPL4
chr19
10251901
10260055
+
MRPS10
chr6
42206807
42217861
-
MUC4
chr3
195746765
195811973
-
NBN
chr8
89933336
90003228
-
PARK7
chr1
7954291
7985505
+
RNF130
chr5
179911651
180072113
-
RNF31
chr14
24146683
24160660
+
RPL18
chr19
48615328
48619184
-
RPS9
chr19
54200809
54249003
+
SDC3
chr1
30869466
30908758
-
SDHAF4
chr6
70566917
70589569
+
SEMA5B
chr3
122909082
123028605
-
SIGIRR
chr11
405716
417455
-
SIVA1
chr14
104753147
104768494
+
TARDBP
chr1
11012344
11026420
+
TMEM259
chr19
1009648
1021179
-
TSC22D4
chr7
100463359
100479232
-
TTI1
chr20
37983007
38033461
-
UBC
chr12
124911604
124917368
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.