Entry Detail


General Information

Database ID:exR0510860
RNA Name:ACOT7
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):6264269End Site(bp):6394391
External Links:ENSG00000097021



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HMGA1
chr6
34236873
34246231
+
CHAMP1
chr13
114314482
114337626
+
ANKZF1
chr2
219229783
219236679
+
PRR7
chr5
177446445
177456286
+
PGS1
chr17
78378649
78425114
+
GYPC
chr2
126656133
126696667
+
UBP1
chr3
33388336
33441371
-
TRIP10
chr19
6737925
6751530
+
MTRNR2L11
chr1
237943724
237945275
-
CCT7
chr2
73233420
73253021
+
SEMA7A
chr15
74409289
74433958
-
TLE3
chr15
70047790
70098176
-
GJA1
chr6
121435595
121449727
+
NAP1L1
chr12
76036585
76084958
-
UBE2D2
chr5
139526431
139628434
+
PPP6R1
chr19
55229779
55259017
-
CUL4A
chr13
113208193
113267108
+
EPB41L3
chr18
5392381
5630700
-
FXR1
chr3
180868141
180982753
+
CSNK2A1
chr20
472498
543835
-
ELP2
chr18
36129444
36180557
+
OGT
chrX
71533104
71575892
+
EEF2
chr19
3976056
3985463
-
MLYCD
chr16
83899115
83951445
+
ZNF675
chr19
23525631
23687220
-
SHC1
chr1
154962298
154974395
-
SLC25A6
chrX
1386152
1392113
-
ZNF333
chr19
14689801
14733746
+
RBM15B
chr3
51391285
51397908
+
TRIM11
chr1
228393673
228406835
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-155-5p
chr21
25573983
25574006
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC116407.1
chr17
32141226
32143135
-
AL117378.1
chr6
131901963
131920565
+
AC009119.2
chr16
83929796
83931223
-
AL139393.2
chr6
160926269
160943110
+
DANCR
chr4
52712404
52720351
+
FGD5-AS1
chr3
14920347
14948424
-
MIR155HG
chr21
25561909
25575168
+
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.