Entry Detail


General Information

Database ID:exR0510863
RNA Name:ACOX1
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):75941507End Site(bp):75979177
External Links:ENSG00000161533



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RPS19
chr19
41860255
41872925
+
SAP18
chr13
21140514
21149084
+
LAMA3
chr18
23689443
23956222
+
ZNF512
chr2
27582969
27623217
+
ELAC2
chr17
12991612
13018065
-
C3orf52
chr3
112086335
112131004
+
MAZ
chr16
29806106
29811164
+
POU5F1
chr6
31164337
31180731
-
ZNF544
chr19
58228594
58277495
+
NUP205
chr7
135557917
135648757
+
OPA1
chr3
193593144
193697811
+
KIF14
chr1
200551497
200620751
-
WDR26
chr1
224385143
224437033
-
ELF4
chrX
130064874
130110716
-
ASXL1
chr20
32358330
32439319
+
NRF1
chr7
129611720
129757082
+
SMC3
chr10
110567691
110604636
+
OSBPL10
chr3
31657890
32077580
-
PSAP
chr10
71816298
71851325
-
TOX4
chr14
21476597
21499175
+
PPP6R1
chr19
55229779
55259017
-
RPL13A
chr19
49487554
49492308
+
TNFRSF13B
chr17
16929816
16972118
-
MREG
chr2
215942584
216034096
-
NDUFV1
chr11
67605653
67612554
+
PPM1G
chr2
27381195
27409591
-
HLA-A
chr6
29941260
29945884
+
NOP14
chr4
2937933
2963406
-
DCTPP1
chr16
30423615
30430030
-
RPL10L
chr14
46651010
46651781
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC138761.1
chr17
22266395
22288301
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.