Entry Detail


General Information

Database ID:exR0510866
RNA Name:ACOXL
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):110732573End Site(bp):111118222
External Links:ENSG00000153093



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BASP1
chr5
17065598
17276843
+
CTSA
chr20
45890144
45898820
+
DAG1
chr3
49468703
49535618
+
FBXO22
chr15
75903876
75942511
+
LCK
chr1
32251239
32286165
+
NAV1
chr1
201622885
201826969
+
OXLD1
chr17
81665036
81666635
-
PFN1
chr17
4945652
4949061
-
RHBDD2
chr7
75842602
75888926
+
RNF213
chr17
80260866
80398786
+
SBF1
chr22
50445000
50475035
-
SSTR3
chr22
37204237
37212477
-
TM9SF4
chr20
32109714
32167258
+
ZNF106
chr15
42412823
42491141
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.