Entry Detail


General Information

Database ID:exR0510869
RNA Name:ACP6
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):147629652End Site(bp):147670524
External Links:ENSG00000162836



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABHD12
chr20
25294742
25390835
-
ACSL1
chr4
184755595
184826818
-
BICD2
chr9
92711363
92764833
-
CHERP
chr19
16517894
16542437
-
CHRNB1
chr17
7445061
7457710
+
COX4I1
chr16
85798633
85807068
+
CPSF1
chr8
144393229
144409335
-
DERL3
chr22
23834503
23839128
-
DST
chr6
56457987
56954649
-
FBXO4
chr5
41925254
41941743
+
GDE1
chr16
19501693
19522123
-
GLCE
chr15
69160584
69272217
+
GLIS3
chr9
3824127
4348392
-
IFITM1
chr11
313506
315272
+
IFITM2
chr11
307631
315272
+
NUP214
chr9
131125586
131234663
+
PARP14
chr3
122680839
122730840
+
PCNA
chr20
5114953
5126626
-
PHF21B
chr22
44881162
45010005
-
PKM
chr15
72199029
72231822
-
PPRC1
chr10
102132994
102150333
+
RPL11
chr1
23691742
23696835
+
RPL5
chr1
92832013
92841924
+
SCD
chr10
100347233
100364826
+
TGFBRAP1
chr2
105264391
105329735
-
TRAM2
chr6
52497408
52577060
-
TUBG2
chr17
42659284
42667006
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC113189.4
chr17
7439506
7445966
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.