exRNAdisease

Entry Detail

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General Information

Database ID: exR0510890 RNA Name: ACTB RNA Type: mRNA Chromosome: chr7 Starnd: - Coordinate: Start Site(bp): 5527148 End Site(bp): 5563784 External Links: ENSG00000075624

Disease Information

Disease Name: Lactation Disease Category: Other Diseases MeSH ID: D007774 Type: Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena Alias: Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations

Expression Detail

GEO ID: GSE36936 Description: Gene Expression in the Human Mammary Epithelium during Initiation of Lactation. Experimental Design: Time Series Case Disease Type: Lactation Case Disease SubType: NA Case Sample: 12h post delivery Control Sample: 6h post delivery Number of Case: 7 Number of Control: 7 Number of Samples: 14

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ACTN1 chr14 68874143 68979440 - AIP chr11 67483026 67491103 + ACAT1 chr11 108116695 108147603 + ACIN1 chr14 23058564 23095614 - AC138894.1 chr16 28456371 28492098 - ACTA2 chr10 88935074 88991339 - AAMP chr2 218264123 218270257 - ADPGK chr15 72751369 72785846 - AC068946.2 chr2 219209772 219222738 - AC104452.1 chr3 49416777 49429314 - AC010132.3 chr7 42909273 42932174 - ACTR10 chr14 58200080 58235636 + ADAM8 chr10 133262420 133276868 - ALDOA chr16 30064164 30070457 + AC011448.1 chr19 19516227 19536076 + AC012184.2 chr16 70299194 70372582 + AL109827.1 chr20 35632340 35674544 - ABCF1 chr6 30571393 30597179 + AC124312.1 chr15 24955034 25000276 + AC098850.3 chr17 16690261 16804453 + ACLY chr17 41866917 41930542 - ACTBL2 chr5 57480018 57482811 - AC010463.1 chr19 17267418 17282966 + AKIRIN1 chr1 38991276 39006059 + ABCB7 chrX 75051048 75156732 - AC010422.3 chr19 12643831 12648397 - AC015813.2 chr17 57989038 58007246 - ACTN4 chr19 38647649 38731589 + AD000671.2 chr19 35739252 35745432 - AL136295.4 chr14 24180395 24190416 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-155-5p chr21 25573983 25574006 + hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-7847-3p chr11 1880105 1880125 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AD000090.1 chr19 35557956 35581954 + AC013269.1 chr2 130530275 130537182 + AC007326.5 chr22 18936411 18947741 + AL139819.1 chr10 100335563 100346390 - HOXC-AS2 chr12 53993810 53996785 - AC087190.3 chr16 9104848 9113181 + LINC01641 chr1 227393554 227431035 + SNHG5 chr6 85650491 85678932 - OIP5-AS1 chr15 41283990 41309737 + AC091564.7 chr11 6610883 6616594 - AC079466.1 chr19 28606688 28615229 + SNHG6 chr8 66921684 66926398 - SNHG22 chr18 49814023 49851059 + AC139149.1 chr17 81514047 81527776 + MIR155HG chr21 25561909 25575168 + AL023653.1 chrX 129794994 129796963 + AC098850.4 chr17 16788057 16816540 + AL356488.2 chr1 109100193 109100619 + AC004943.1 chr16 72805998 72809872 + AC016876.2 chr17 7581964 7584086 - AC079781.5 chr7 97851688 97972985 - GAS5 chr1 173858559 173868882 - AL359924.1 chr1 237862175 237928321 + LINC01896 chr18 78976555 78979074 - AC055811.1 chr17 17167946 17185554 - AC079949.1 chr12 127142029 127146532 - ESRG chr3 54632122 54639857 - LINC00662 chr19 27681072 27794005 - AL022311.1 chr22 37876148 37895563 + TERC chr3 169764520 169765060 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22649065 Title: Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans Author: Mohammad MA, Hadsell DL, Haymond MW. Journal: Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76. Description: We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.