Entry Detail


General Information

Database ID:exR0510894
RNA Name:ACTG2
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):73892314End Site(bp):73919865
External Links:ENSG00000163017



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
POTEE
chr2
131218067
131265278
+
ACTG1
chr17
81509971
81523847
-
GADD45A
chr1
67685201
67688334
+
LSM11
chr5
157743712
157760709
+
NGRN
chr15
90265659
90278141
+
MTRNR2L1
chr17
22523111
22524663
+
CNN1
chr19
11538767
11550323
+
BOLA1
chr1
149887890
149900798
+
NBEAL1
chr2
203014879
203226378
+
HNRNPA2B1
chr7
26173057
26201529
-
LRPPRC
chr2
43886224
43995989
-
SNX17
chr2
27370496
27377535
+
PPIG
chr2
169584344
169641406
+
SLC25A3
chr12
98593591
98606379
+
SYPL1
chr7
106090503
106112576
-
MCM3AP
chr21
46235133
46286297
-
POTEI
chr2
130459455
130509707
-
ACTA2
chr10
88935074
88991339
-
COMT
chr22
19941733
19969975
+
RAB10
chr2
26034084
26137454
+
ANP32A
chr15
68778535
68820897
-
ASB3
chr2
53532672
53860160
-
PKM
chr15
72199029
72231822
-
CAMP
chr3
48223347
48225491
+
POTEJ
chr2
130611481
130658091
+
SDHA
chr5
218241
257082
+
HSP90B1
chr12
103930107
103953645
+
WNT5B
chr12
1529891
1647212
+
ACTB
chr7
5527148
5563784
-
ACTC1
chr15
34790230
34795549
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC013269.1
chr2
130530275
130537182
+
AL359924.1
chr1
237862175
237928321
+
EIF1B-AS1
chr3
40061110
40309698
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.