Entry Detail


General Information

Database ID:exR0510902
RNA Name:ACTR10
RNA Type:mRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):58200080End Site(bp):58235636
External Links:ENSG00000131966



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HIBCH
chr2
190189735
190344193
-
CCNG1
chr5
163437569
163446151
+
PPP2CA
chr5
134194332
134226073
-
TOMM20
chr1
235109341
235128837
-
ACTB
chr7
5527148
5563784
-
APP
chr21
25880550
26171128
-
PTK2B
chr8
27311482
27459391
+
CTDSP2
chr12
57819927
57846729
-
SLC6A9
chr1
43991500
44031467
-
B2M
chr15
44711487
44718877
+
RPS20
chr8
56067295
56074581
-
NUDC
chr1
26900238
26946871
+
AURKA
chr20
56369389
56392337
-
PABPC3
chr13
25095868
25099254
+
TUBA3C
chr13
19173772
19181824
-
UBA6
chr4
67612652
67701155
-
CAND1
chr12
67269358
67319953
+
MGRN1
chr16
4616493
4690974
+
ARF1
chr1
228082660
228099212
+
ALDOA
chr16
30064164
30070457
+
MTRNR2L12
chr3
96617188
96618236
-
PBX1
chr1
164555584
164899296
+
PRKCI
chr3
170222424
170305977
+
LRRC20
chr10
70298970
70382650
-
CCNC
chr6
99542387
99568825
-
SMARCC1
chr3
47585269
47782106
-
TSPAN15
chr10
69451465
69507666
+
NID1
chr1
235975830
236065109
-
CAMK2G
chr10
73812501
73874591
-
AIF1L
chr9
131096476
131123152
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.