Entry Detail


General Information

Database ID:exR0510903
RNA Name:ACTR1A
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):102461881End Site(bp):102502712
External Links:ENSG00000138107



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACTR1B
chr2
97655939
97664044
-
AP002990.1
chr11
62559603
62591531
-
PPP3R1
chr2
68178857
68256237
-
MT-ND3
chrMT
10059
10404
+
CDK19
chr6
110609978
110815958
-
ERC2
chr3
55508311
56468467
-
MT-ND1
chrMT
3307
4262
+
INO80
chr15
40978880
41116280
-
TCOF1
chr5
150357629
150400308
+
OS9
chr12
57693955
57721557
+
GOLGA7
chr8
41490396
41510980
+
PAPOLA
chr14
96501433
96567111
+
IGFBP2
chr2
216632828
216664436
+
RPL27A
chr11
8682788
8714759
+
PDE7A
chr8
65717510
65842322
-
RPS6
chr9
19375715
19380236
-
HNRNPL
chr19
38836388
38852347
-
MT-ND4
chrMT
10760
12137
+
EIF5AL1
chr10
79512601
79516440
+
COMMD10
chr5
116085016
116412762
+
TMSB4X
chrX
12975110
12977227
+
RPL29
chr3
51993522
51995895
-
CBSL
chr21
6444869
6468040
-
GGCT
chr7
30496621
30504841
-
ARHGEF19
chr1
16197854
16212652
-
SAE1
chr19
47113274
47210636
+
TRIM28
chr19
58544064
58550722
+
CHST14
chr15
40470998
40474571
+
TBCB
chr19
36114289
36125947
+
CREBL2
chr12
12611827
12645108
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-363-3p
chrX
134169382
134169403
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC011297.1
chrY
6918682
6920791
+
AC027020.2
chr15
100547765
100550153
-
AC245014.3
chr1
145281116
145281462
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.