Entry Detail


General Information

Database ID:exR0510906
RNA Name:ACTR3
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):113890063End Site(bp):113962596
External Links:ENSG00000115091



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CD53
chr1
110871188
110899922
+
PTPRCAP
chr11
67435510
67437682
-
GLI1
chr12
57459785
57472268
+
MT-ATP6
chrMT
8527
9207
+
EZR
chr6
158765741
158819368
-
PGRMC2
chr4
128269237
128288829
-
RPL11
chr1
23691742
23696835
+
TRIM27
chr6
28903002
28923988
-
RPL4
chr15
66498015
66524532
-
TEAD3
chr6
35473597
35497079
-
ERLIN1
chr10
100150094
100186033
-
SF3A1
chr22
30331988
30356919
-
MARS2
chr2
197705369
197708395
+
AC245033.1
chr15
82536788
82573194
-
CENPI
chrX
101098218
101163681
+
ERG28
chr14
75649791
75660876
-
PSMD8
chr19
38374536
38383824
+
NUMA1
chr11
72002864
72080693
-
DSTN
chr20
17570075
17609919
+
UBE2D3
chr4
102794383
102868896
-
TSPAN33
chr7
129144707
129169699
+
RPS29
chr14
49570984
49599164
-
DDB1
chr11
61299451
61342596
-
ERGIC3
chr20
35542021
35557634
+
CCT8
chr21
29055805
29073797
-
MLXIPL
chr7
73593194
73624543
-
HLA-DRB5
chr6
32517353
32530287
-
PCBP2
chr12
53452102
53481162
+
MEX3A
chr1
156072013
156082465
-
ATPAF1
chr1
46632737
46673867
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AC245033.4
chr15
82533175
82540008
-
AL035458.2
chr20
34234840
34281173
-
AC093734.1
chr7
1508655
1509427
-
GAS5
chr1
173858559
173868882
-
MALAT1
chr11
65497688
65506516
+
TMEM147-AS1
chr19
35540738
35546029
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.