Entry Detail


General Information

Database ID:exR0510913
RNA Name:ACVR1
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):157736444End Site(bp):157876330
External Links:ENSG00000115170



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BCAT1
chr12
24810024
24949101
-
BRINP1
chr9
119153458
119369435
-
CIT
chr12
119685791
119877320
-
EIF4B
chr12
53006158
53042209
+
EWSR1
chr22
29268009
29300525
+
IFITM2
chr11
307631
315272
+
KPNA4
chr3
160495007
160565571
-
MAZ
chr16
29806106
29811164
+
MRPS5
chr2
95085369
95149434
-
MT-CO3
chrMT
9207
9990
+
NSL1
chr1
212726153
212791782
-
PEF1
chr1
31629866
31644896
-
RPS27A
chr2
55231903
55235853
+
SKAP2
chr7
26667068
26995239
-
TCF12
chr15
56918623
57299281
+
ZBED6
chr1
203795714
203854999
+
ZC3H11A
chr1
203795654
203854999
+
ZNF468
chr19
52838010
52857649
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-876-5p
chr9
28863675
28863696
-
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.