Entry Detail


General Information

Database ID:exR0510914
RNA Name:ACVR1B
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):51951699End Site(bp):51997078
External Links:ENSG00000135503



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HIBADH
chr7
27525442
27662883
-
LRRC42
chr1
53946085
53968168
+
SNURF
chr15
24954986
24977850
+
RPL5
chr1
92832013
92841924
+
WDR62
chr19
36054881
36105108
+
RANBP2
chr2
108719482
108785809
+
SLC7A6
chr16
68264516
68301823
+
RPL18
chr19
48615328
48619184
-
C9orf64
chr9
83938311
83956986
-
ST6GAL1
chr3
186930502
187078553
+
PPFIA4
chr1
203026498
203078740
+
ZNF592
chr15
84748592
84806445
+
TSPAN6
chrX
100627108
100639991
-
MFGE8
chr15
88898683
88913381
-
BAZ2A
chr12
56595596
56636816
-
DGAT1
chr8
144314584
144326910
-
FZD3
chr8
28494205
28574267
+
SMG5
chr1
156249224
156282825
-
NMT1
chr17
45051610
45109016
+
SETD2
chr3
47016429
47163967
-
HACD3
chr15
65530418
65578349
+
TAOK2
chr16
29973868
29992261
+
CNPY3
chr6
42929192
42939294
+
ABCB6
chr2
219209772
219218994
-
RPL26
chr17
8377516
8383213
-
DUSP3
chr17
43766125
43778977
-
SYNGR2
chr17
78168558
78173527
+
SSBP4
chr19
18418864
18434562
+
AC010422.3
chr19
12643831
12648397
-
PCNT
chr21
46324141
46445769
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-7-5p
chr19
4770700
4770723
+
hsa-miR-143-3p
chr5
149428978
149428998
+
hsa-miR-9-5p
chr5
88666902
88666924
-
hsa-miR-136-5p
chr14
100884716
100884738
+
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-342-3p
chr14
100109715
100109737
+
hsa-miR-769-5p
chr19
46018961
46018982
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-760
chr1
93846880
93846899
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
AC135178.2
chr17
8318088
8318712
-
DANCR
chr4
52712404
52720351
+
NEAT1
chr11
65422774
65445540
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.