Entry Detail


General Information

Database ID:exR0510922
RNA Name:ADA
RNA Type:mRNA
Chromosome:chr20
Starnd:-
Coordinate:
Start Site(bp):44619522End Site(bp):44652233
External Links:ENSG00000196839



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
S100A11
chr1
152032506
152047907
-
ELOVL5
chr6
53267398
53349179
-
SSR4
chrX
153793516
153798499
+
HSP90AB1
chr6
44246166
44253888
+
WASHC3
chr12
102012840
102062149
-
RAB14
chr9
121178133
121223014
-
LAT2
chr7
74199652
74229834
+
EEF1A1
chr6
73515750
73523797
-
CDKN1A
chr6
36676460
36687339
+
ZNF703
chr8
37695782
37700019
+
NACA
chr12
56712427
56731628
-
SEC62
chr3
169966635
169998373
+
HLA-C
chr6
31268749
31272130
-
SRSF4
chr1
29147743
29181900
-
URB1
chr21
32311018
32393012
-
GYPC
chr2
126656133
126696667
+
PEX5
chr12
7188685
7218574
+
AGAP3
chr7
151085831
151144436
+
XRCC5
chr2
216107464
216206303
+
DVL2
chr17
7225342
7234517
-
RPS19
chr19
41860255
41872925
+
EVL
chr14
99971449
100144236
+
MRPL38
chr17
75898643
75905413
-
RPL27A
chr11
8682788
8714759
+
RALY
chr20
33993646
34108308
+
TUBA1B
chr12
49127782
49131397
-
NPC2
chr14
74476192
74494177
-
CD81
chr11
2376177
2397419
+
DRAP1
chr11
65919274
65921563
+
SORD
chr15
45023181
45077185
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL359924.1
chr1
237862175
237928321
+
LINC00996
chr7
150433654
150448140
+
SNHG1
chr11
62851984
62855953
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.