Entry Detail


General Information

Database ID:exR0510925
RNA Name:ADAL
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):43330657End Site(bp):43354555
External Links:ENSG00000168803



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EIF2S3
chrX
24054946
24078810
+
EIF4B
chr12
53006158
53042209
+
GINS4
chr8
41529218
41545030
+
HLA-F
chr6
29722775
29738528
+
MZB1
chr5
139387467
139390081
-
NADK
chr1
1751232
1780457
-
PIGS
chr17
28553383
28571794
-
RNF24
chr20
3927309
4015558
-
RPL10
chrX
154389955
154409168
+
RPL13
chr16
89560657
89566828
+
RPL37A
chr2
216498825
216579180
+
SALL2
chr14
21521080
21537216
-
SERINC1
chr6
122443351
122471807
-
SFRP2
chr4
153780591
153789083
-
UAP1L1
chr9
137077517
137084539
+
WDR62
chr19
36054881
36105108
+
ZNF431
chr19
21142024
21196053
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.