Entry Detail


General Information

Database ID:exR0510927
RNA Name:ADAM11
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):44758988End Site(bp):44781846
External Links:ENSG00000073670



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AGRN
chr1
1020120
1056118
+
CREBZF
chr11
85659708
85682908
-
CSDE1
chr1
114716913
114758676
-
FANCA
chr16
89737549
89816657
-
GHDC
chr17
42188799
42194532
-
GOLPH3
chr5
32124716
32174319
-
HCFC1
chrX
153947557
153971818
-
HDGFL3
chr15
83112738
83207823
-
KIAA1841
chr2
61065871
61138034
+
LMNB2
chr19
2427638
2456959
-
LRP6
chr12
12116025
12267044
-
MCC
chr5
113022099
113488823
-
MDC1
chr6
30699807
30717447
-
MDGA1
chr6
37630679
37699306
-
MT-ND1
chrMT
3307
4262
+
NISCH
chr3
52455118
52493068
+
NOP53
chr19
47745546
47757058
+
PLXNA1
chr3
126988594
127037392
+
SF3B3
chr16
70523791
70577670
+
SNX17
chr2
27370496
27377535
+
TLE3
chr15
70047790
70098176
-
TM9SF2
chr13
99446311
99564048
+
TMEM25
chr11
118531041
118547280
+
TNPO2
chr19
12699194
12724011
-
TUBB
chr6
30720352
30725426
+
UNC119B
chr12
120710458
120723640
+
YBX1
chr1
42682418
42703805
+
ZNF70
chr22
23738682
23751112
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
LINC02228
chr5
25087450
25190956
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.