Entry Detail


General Information

Database ID:exR0510929
RNA Name:ADAM15
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):155050566End Site(bp):155062775
External Links:ENSG00000143537



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NNT
chr5
43602692
43707405
+
PCSK1N
chrX
48831096
48835610
-
RBM26
chr13
79311824
79406477
-
AC096887.1
chr3
52969119
53099453
-
DSG2
chr18
31498177
31549008
+
NR3C1
chr5
143277931
143435512
-
SF3A2
chr19
2236824
2248655
+
MKI67
chr10
128096659
128126423
-
HDHD5
chr22
17137511
17165287
-
VAMP7
chrX
155881345
155943769
+
CBFB
chr16
67028984
67101058
+
DYNLL2
chr17
58083419
58095542
+
KIFC1
chr6
33391823
33409896
+
SIGMAR1
chr9
34634722
34637809
-
MTRNR2L12
chr3
96617188
96618236
-
CNOT9
chr2
218568580
218597080
+
OTUD4
chr4
145110838
145180589
-
ATG4B
chr2
241637213
241673857
+
WNK1
chr12
752579
911452
+
LTBP1
chr2
32946953
33399509
+
MTHFD1
chr14
64388031
64463457
+
ALDOA
chr16
30064164
30070457
+
APEX1
chr14
20455191
20457772
+
TNRC18
chr7
5306790
5425414
-
HK1
chr10
69269984
69401884
+
MARCKS
chr6
113857345
113863475
+
SETD6
chr16
58515479
58521181
+
PAX9
chr14
36657568
36679362
+
NEK6
chr9
124257606
124353307
+
PCYOX1L
chr5
149358037
149369653
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.