Entry Detail


General Information

Database ID:exR0510931
RNA Name:ADAM19
RNA Type:mRNA
Chromosome:chr5
Starnd:-
Coordinate:
Start Site(bp):157395534End Site(bp):157575775
External Links:ENSG00000135074



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AGO4
chr1
35808016
35857890
+
AICDA
chr12
8602170
8612867
-
BZW1
chr2
200810594
200827338
+
CALM3
chr19
46601074
46610782
+
DDX17
chr22
38483438
38507660
-
EIF3J
chr15
44537125
44563029
+
FKBP1A
chr20
1368978
1393172
-
FOCAD
chr9
20658309
20995955
+
GTF3C2
chr2
27325849
27357034
-
IGFBP2
chr2
216632828
216664436
+
LRP5L
chr22
25351418
25405377
-
MGST3
chr1
165631213
165661796
+
MYH9
chr22
36281277
36388067
-
NDST1
chr5
150485818
150558211
+
PRDX5
chr11
64318121
64321811
+
PSMD8
chr19
38374536
38383824
+
PTPN6
chr12
6946468
6961316
+
RAB1B
chr11
66268590
66277492
+
RNF5
chr6
32178405
32180793
+
RPL13
chr16
89560657
89566828
+
SLC38A1
chr12
46183063
46270017
-
SMARCA4
chr19
10960825
11079426
+
STMN1
chr1
25884181
25906991
-
TATDN2
chr3
10248023
10281218
+
TMEM60
chr7
77793728
77798434
-
VPS18
chr15
40894450
40903975
+
ZNF354B
chr5
178859953
178888122
+
ZNHIT2
chr11
65116403
65117701
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.