Entry Detail


General Information

Database ID:exR0510979
RNA Name:ADCY3
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):24819169End Site(bp):24919839
External Links:ENSG00000138031



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
COL4A5
chrX
108439844
108697545
+
GPC3
chrX
133535745
133985594
-
ERCC2
chr19
45349837
45370918
-
HNRNPL
chr19
38836388
38852347
-
GMPR
chr6
16238587
16295549
+
MED12
chrX
71118556
71142454
+
PIEZO2
chr18
10666483
11148762
-
PIP5K1C
chr19
3630183
3700479
-
MTRR
chr5
7851186
7906025
+
IMP4
chr2
130342877
130347967
+
PEX2
chr8
76980258
77001044
-
RPL4
chr15
66498015
66524532
-
CCDC47
chr17
63745255
63776351
-
HIGD1A
chr3
42784298
42804531
-
CYTH1
chr17
78674048
78782297
-
MSC
chr8
71841549
71844468
-
LCOR
chr10
96832282
96995959
+
KIF1A
chr2
240713761
240821036
-
SESN3
chr11
95165513
95232541
-
RHOC
chr1
112701106
112707434
-
WDR81
chr17
1716523
1738599
+
FAM8A1
chr6
17600302
17611715
+
RAN
chr12
130872037
130877678
+
ANO8
chr19
17323223
17334855
-
AKT2
chr19
40230317
40285536
-
POTEF
chr2
130073535
130129222
-
GNB1
chr1
1785285
1891117
-
PIH1D1
chr19
49446298
49453497
-
NFE2L1
chr17
48048329
48061545
+
AL049629.2
chr11
33698261
33722467
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-367-3p
chr4
112647877
112647898
-
hsa-miR-92b-3p
chr1
155195237
155195258
+
hsa-miR-155-3p
chr21
25574022
25574043
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC073062.1
chr2
13537673
13609168
+
AC099329.1
chr3
42785087
42852428
-
AL160408.3
chr1
234669523
234696153
-
LINC01866
chr2
16970034
16974497
+
MEF2C-AS1
chr5
88883328
89466398
+
MIR155HG
chr21
25561909
25575168
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.