Entry Detail


General Information

Database ID:exR0510981
RNA Name:ADCY5
RNA Type:mRNA
Chromosome:chr3
Starnd:-
Coordinate:
Start Site(bp):123282296End Site(bp):123449758
External Links:ENSG00000173175



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RPS6
chr9
19375715
19380236
-
PELP1
chr17
4669774
4704337
-
PHF3
chr6
63635820
63779336
+
AC010422.3
chr19
12643831
12648397
-
GCN1
chr12
120127202
120194715
-
PINK1
chr1
20633458
20651511
+
TUBB2A
chr6
3153666
3157544
-
HSP90AA1
chr14
102080738
102139699
-
GPRC5C
chr17
74424851
74451653
+
RHOB
chr2
20447074
20449440
+
LRFN3
chr19
35935358
35946624
+
AC008878.1
chr19
7507052
7519622
+
DGKZ
chr11
46332905
46380554
+
AL136295.5
chr14
24147548
24166452
+
MRPL36
chr5
1798385
1801366
-
RPL3
chr22
39312882
39320389
-
ICE2
chr15
60419609
60479160
-
FAM83D
chr20
38926312
38953106
+
STK39
chr2
167954020
168247595
-
THOC5
chr22
29505879
29555216
-
ACOT7
chr1
6264269
6394391
-
JPT2
chr16
1678256
1702280
+
ZNF358
chr19
7515292
7521025
+
TUBA1B
chr12
49127782
49131397
-
SKAP2
chr7
26667068
26995239
-
RCC2
chr1
17406760
17439677
-
ZNF253
chr19
19865882
19894674
+
SLC37A3
chr7
140293693
140404433
-
STK10
chr5
172042079
172188224
-
RPL8
chr8
144789765
144792587
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC092902.2
chr3
125774714
125797953
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.