Entry Detail


General Information

Database ID:exR0510982
RNA Name:ADCY6
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):48766194End Site(bp):48789037
External Links:ENSG00000174233



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MACF1
chr1
39081316
39487177
+
SLC25A29
chr14
100291116
100306547
-
HSP90AB1
chr6
44246166
44253888
+
CALM1
chr14
90396502
90408268
+
PRRT4
chr7
128350325
128361685
-
LCMT1
chr16
25111731
25178231
+
FLNA
chrX
154348524
154374638
-
TPM4
chr19
16067021
16103002
+
FADS2
chr11
61792980
61867354
+
MYBBP1A
chr17
4538897
4555631
-
UBB
chr17
16380798
16382745
+
RNF167
chr17
4940008
4945222
+
PUS1
chr12
131929200
131945896
+
LRCH4
chr7
100574011
100586129
-
SELENOP
chr5
42799880
42887392
-
ARID1A
chr1
26693236
26782104
+
PEX19
chr1
160276812
160286348
-
IGF2
chr11
2129112
2141238
-
FNDC3B
chr3
172039578
172401669
+
HUWE1
chrX
53532096
53686728
-
PDCD7
chr15
65117379
65133808
-
LENG8
chr19
54448887
54462037
+
SYNM
chr15
99098217
99135593
+
EME2
chr16
1772810
1781708
+
FNTB
chr14
64986895
65062652
+
SMARCD1
chr12
50085200
50100707
+
SNTB2
chr16
69187129
69309052
+
ZNF628
chr19
55476617
55484487
+
SNRPF
chr12
95858928
95903828
+
TAZ
chrX
154411524
154421726
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC069281.2
chr7
100572232
100578700
-
AC138761.1
chr17
22266395
22288301
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.