Entry Detail


General Information

Database ID:exR0510986
RNA Name:ADD1
RNA Type:mRNA
Chromosome:chr4
Starnd:+
Coordinate:
Start Site(bp):2843857End Site(bp):2930076
External Links:ENSG00000087274



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HIRA
chr22
19330698
19447450
-
DDX17
chr22
38483438
38507660
-
HNRNPAB
chr5
178204533
178211163
+
ENO1
chr1
8861000
8879190
-
MFSD14A
chr1
100038095
100083377
+
RABGAP1L
chr1
174159410
174995308
+
MARCKSL1
chr1
32333839
32336233
-
MTERF4
chr2
241072169
241102332
-
EIF3L
chr22
37848868
37889407
+
CDC123
chr10
12195965
12250589
+
RPS10
chr6
34417454
34426069
-
PDHA2
chr4
95840093
95841464
+
RPL9
chr4
39452521
39458949
-
NPM1
chr5
171387116
171411137
+
IFI44L
chr1
78619922
78646145
+
SAMD11
chr1
923928
944581
+
B2M
chr15
44711487
44718877
+
POLE
chr12
132623753
132687376
-
HNRNPUL2
chr11
62712630
62727457
-
ELOC
chr8
73939169
73972287
-
RGL2
chr6
33291654
33298942
-
BIRC2
chr11
102347211
102378670
+
HLA-A
chr6
29941260
29945884
+
RPL4
chr15
66498015
66524532
-
RPS3
chr11
75399515
75422280
+
LPCAT3
chr12
6976185
7018477
-
CARHSP1
chr16
8852942
8869012
-
CAPN15
chr16
527712
554636
+
CLN6
chr15
68206992
68257211
-
RPS27A
chr2
55231903
55235853
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-184
chr15
79209840
79209861
+
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-193a-5p
chr17
31560016
31560037
+
hsa-miR-361-3p
chrX
85903641
85903663
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACVR2B-AS1
chr3
38451027
38454820
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AC009163.4
chr16
75458252
75460017
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.