Entry Detail


General Information

Database ID:exR0510987
RNA Name:ADD2
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):70607618End Site(bp):70768225
External Links:ENSG00000075340



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
COL21A1
chr6
56056590
56394094
-
PRKD3
chr2
37250502
37324808
-
SMIM20
chr4
25861830
25929874
+
CNN3
chr1
94896949
94927223
-
SHISA5
chr3
48467798
48504826
-
PRUNE1
chr1
151008420
151035713
+
FUBP3
chr9
130578965
130638352
+
YWHAB
chr20
44885702
44908532
+
USP40
chr2
233475520
233566782
-
DYNC1H1
chr14
101964573
102056443
+
YIPF4
chr2
32277904
32316594
+
RPS6
chr9
19375715
19380236
-
C12orf75
chr12
105235290
105396097
+
AC138894.1
chr16
28456371
28492098
-
PPID
chr4
158709127
158723396
-
P4HB
chr17
81843161
81860624
-
CMSS1
chr3
99817837
100181732
+
HSP90AB1
chr6
44246166
44253888
+
TREX2
chrX
153444720
153470587
-
AAK1
chr2
69457997
69674349
-
RPL11
chr1
23691742
23696835
+
MAP3K3
chr17
63622415
63696303
+
ANKRD13C
chr1
70258999
70354734
-
ATP5F1D
chr19
1241746
1244825
+
GDF11
chr12
55743122
55757264
+
ZMIZ2
chr7
44748581
44769881
+
SRSF9
chr12
120461672
120469748
-
SHMT1
chr17
18327860
18363563
-
RPL4
chr15
66498015
66524532
-
GTPBP1
chr22
38705742
38738299
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC245014.3
chr1
145281116
145281462
+
AL356489.2
chr9
33697459
33700986
+
FOXD3-AS1
chr1
63320884
63324441
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.