Entry Detail


General Information

Database ID:exR0510988
RNA Name:ADD3
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):109996368End Site(bp):110135565
External Links:ENSG00000148700



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ZNF90
chr19
20077994
20127076
+
SLC2A3
chr12
7919230
7936187
-
C16orf72
chr16
9091644
9121635
+
SMARCB1
chr22
23786931
23838008
+
MAGI1
chr3
65353525
66038834
-
STK26
chrX
132023302
132075943
+
GGH
chr8
63015079
63038806
-
AASS
chr7
122073549
122144255
-
AC011462.1
chr19
41350853
41425001
+
COPS3
chr17
17246616
17281273
-
HDGF
chr1
156742109
156766925
-
ATP6V1G1
chr9
114587769
114598879
+
TIMELESS
chr12
56416363
56449426
-
CNTNAP2
chr7
146116002
148420998
+
CNTN2
chr1
205042937
205078289
+
TBCD
chr17
82752065
82945914
+
TM9SF4
chr20
32109714
32167258
+
EXOSC8
chr13
36998816
37009614
+
KHNYN
chr14
24429286
24441843
+
CLTA
chr9
36190856
36304781
+
MEST
chr7
130486171
130506465
+
MT-CO1
chrMT
5904
7445
+
SELENOF
chr1
86862445
86914424
-
TOX4
chr14
21476597
21499175
+
TMED5
chr1
93149742
93180516
-
HILPDA
chr7
128455849
128458418
+
BCAS3
chr17
60677453
61392838
+
RBMX
chrX
136848004
136880764
-
MRPS23
chr17
57834781
57850056
-
TPT1
chr13
45333471
45341370
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC020928.1
chr19
36773112
36777078
+
MALAT1
chr11
65497688
65506516
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.