Entry Detail


General Information

Database ID:exR0510993
RNA Name:ADH5
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):99070978End Site(bp):99088801
External Links:ENSG00000197894



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
GALNT2
chr1
230057990
230282122
+
CLPTM1
chr19
44954585
44993341
+
BUB1B
chr15
40161023
40221136
+
MAD1L1
chr7
1815793
2233243
-
PSAP
chr10
71816298
71851325
-
RSAD1
chr17
50478860
50485974
+
PTPN6
chr12
6946468
6961316
+
ACTR6
chr12
100199122
100241865
+
SRP68
chr17
76038775
76072517
-
CEBPZ
chr2
37201612
37231596
-
SEC61A1
chr3
128051641
128071683
+
TYRO3
chr15
41557675
41583589
+
RPS19
chr19
41860255
41872925
+
SMARCA4
chr19
10960825
11079426
+
ILF2
chr1
153661788
153671028
-
NUDCD3
chr7
44379119
44490658
-
SEC22A
chr3
123201927
123274136
+
RAN
chr12
130872037
130877678
+
OTX2
chr14
56799905
56816693
-
RPL15
chr3
23916545
23924374
+
SLX1A
chr16
30193887
30197561
+
C5orf30
chr5
103258763
103278660
+
TUBB
chr6
30720352
30725426
+
WDFY1
chr2
223855716
223945357
-
AL136454.1
chr1
192716132
192716653
+
VIM
chr10
17228241
17237593
+
TAF6
chr7
100107070
100119841
-
HMGA1
chr6
34236873
34246231
+
PABPC1
chr8
100685816
100722809
-
VCL
chr10
73995193
74121363
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-1825
chr20
32237830
32237847
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
C5orf17
chr5
23951348
24178263
+
OXCT1-AS1
chr5
41869927
41872241
+
SLX1A-SULT1A3
chr16
30193892
30204310
+
SNHG15
chr7
44983023
44986961
-
TUG1
chr22
30969245
30979395
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.