Entry Detail


General Information

Database ID:exR0511002
RNA Name:ADM
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):10305073End Site(bp):10307397
External Links:ENSG00000148926



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RASIP1
chr19
48720585
48740610
-
YWHAG
chr7
76326799
76358991
-
SCRIB
chr8
143790920
143815773
-
CARHSP1
chr16
8852942
8869012
-
FAU
chr11
65120630
65122177
-
DOLK
chr9
128945530
128947603
-
TMEM39B
chr1
32072031
32102866
+
ATP13A3
chr3
194402672
194498364
-
PIEZO1
chr16
88715338
88785220
-
MCUB
chr4
109560209
109688719
+
SSR2
chr1
156009048
156020951
-
ARPC3
chr12
110434823
110450422
-
PSMC4
chr19
39971165
39981764
+
THOC3
chr5
175917873
176034680
-
PRELID3B
chr20
59033145
59042809
-
CBX3
chr7
26201162
26213607
+
SNX19
chr11
130875436
130916509
-
STAT1
chr2
190908460
191020960
-
HSP90AB1
chr6
44246166
44253888
+
PSMF1
chr20
1113240
1189415
+
COQ10A
chr12
56266858
56270966
+
SRSF7
chr2
38743599
38751494
-
DDIT4
chr10
72273924
72276036
+
OSGIN2
chr8
89901849
89927888
+
IRS4
chrX
108732482
108736409
-
CENPP
chr9
92325953
92620529
+
LCMT1
chr16
25111731
25178231
+
PACS1
chr11
66070272
66244744
+
ATP1B3
chr3
141876124
141926549
+
EPS15
chr1
51354263
51519266
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-92a-3p
chrX
134169544
134169565
-
hsa-miR-363-3p
chrX
134169382
134169403
-
hsa-miR-367-3p
chr4
112647877
112647898
-
hsa-miR-92b-3p
chr1
155195237
155195258
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC069281.2
chr7
100572232
100578700
-
AC073111.3
chr7
150379329
150410597
+
PAUPAR
chr11
31812307
32002405
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.