Entry Detail


General Information

Database ID:exR0511006
RNA Name:ADO
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):62804720End Site(bp):62808479
External Links:ENSG00000181915



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
B3GNT10
chr9
120792403
120799918
+
PTMA
chr2
231706895
231713541
+
ANAPC15
chr11
72106378
72112780
-
ZNF581
chr19
55635459
55645623
+
MTRNR2L12
chr3
96617188
96618236
-
RPS11
chr19
49496365
49499708
+
UBR5
chr8
102252273
102412759
-
TRAPPC4
chr11
119018763
119025454
+
NOL11
chr17
67717931
67744531
+
GDI2
chr10
5765223
5842132
-
GUF1
chr4
44678420
44700928
+
XPOT
chr12
64404392
64451125
+
YWHAQ
chr2
9583967
9630997
-
E2F5
chr8
85177154
85217158
+
RPS17
chr15
82536750
82540459
-
MBTD1
chr17
51177425
51260163
-
GNAI3
chr1
109548615
109600195
+
NEK9
chr14
75079353
75127344
-
RPS15
chr19
1438358
1440494
+
GRIK2
chr6
101181257
102070083
+
PRRC2A
chr6
31620715
31637771
+
DMTF1
chr7
87152361
87196337
+
ERI3
chr1
44221070
44355260
-
TSN
chr2
121737103
121767853
+
ADK
chr10
74151202
74709963
+
MFGE8
chr15
88898683
88913381
-
UBE2G2
chr21
44768580
44801826
-
HERPUD2
chr7
35632659
35695571
-
CREG1
chr1
167529117
167553805
-
HMGA1
chr6
34236873
34246231
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009163.4
chr16
75458252
75460017
-
KANSL1-AS1
chr17
46193576
46196723
+
MALAT1
chr11
65497688
65506516
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.