Entry Detail


General Information

Database ID:exR0511011
RNA Name:ADPGK
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):72751369End Site(bp):72785846
External Links:ENSG00000159322



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EEF1A1
chr6
73515750
73523797
-
B4GAT1
chr11
66345374
66347629
-
MKNK2
chr19
2037465
2051244
-
UBA2
chr19
34428352
34471251
+
PGK1
chrX
77910739
78129295
+
STAMBP
chr2
73828916
73873659
+
CCDC150
chr2
196639554
196763490
+
SRSF1
chr17
58000919
58007346
-
GTF3C2
chr2
27325849
27357034
-
EIF3H
chr8
116642130
116766925
-
ACTB
chr7
5527148
5563784
-
GMCL1
chr2
69829660
69881384
+
BCAR3
chr1
93561741
93847150
-
UBE2V2
chr8
48008415
48064708
+
MTHFD2
chr2
74198610
74217565
+
MT-CO1
chrMT
5904
7445
+
NOL8
chr9
92297358
92325636
-
EFTUD2
chr17
44849948
44899445
-
PPP1R14B
chr11
64244479
64246943
-
ZFP42
chr4
187995771
188005046
+
ATG4B
chr2
241637213
241673857
+
NDUFB3
chr2
201071433
201085750
+
BCKDK
chr16
31106107
31112791
+
PCBP2
chr12
53452102
53481162
+
MORC4
chrX
106813871
107000212
-
HMGB2
chr4
173331376
173334432
-
SLC25A29
chr14
100291116
100306547
-
TBCA
chr5
77691166
77868780
-
SACS
chr13
23328826
23433740
-
PASK
chr2
241106099
241150264
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC135050.1
chr16
31056460
31062803
+
AL355488.1
chr1
110370154
110373003
+
PCBP2-OT1
chr12
53464468
53465057
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.