Entry Detail


General Information

Database ID:exR0511012
RNA Name:ADPRH
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):119579268End Site(bp):119589945
External Links:ENSG00000144843



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AHCY
chr20
34280268
34311802
-
CFL1
chr11
65823022
65862026
-
COX7A2
chr6
75237675
75250323
-
ECHDC2
chr1
52895910
52927212
-
EDARADD
chr1
236348257
236502915
+
FCER2
chr19
7688758
7702146
-
FTL
chr19
48965309
48966879
+
MFSD12
chr19
3538261
3574290
-
MRM2
chr7
2234195
2242205
-
MRPS26
chr20
3046052
3048250
+
MYO18A
chr17
29071124
29180412
-
NACA2
chr17
61590421
61591219
-
NCL
chr2
231453531
231483641
-
PGRMC1
chrX
119236245
119244466
+
PSME1
chr14
24136163
24138967
+
RACK1
chr5
181236897
181248096
-
RAF1
chr3
12583601
12664226
-
RIOX2
chr3
97941818
97972457
-
RPL37A
chr2
216498825
216579180
+
RPLP0
chr12
120196699
120201235
-
RPS2
chr16
1962058
1964841
-
RPS25
chr11
119015712
119018691
-
RSRC2
chr12
122503454
122527000
-
SIAH2
chr3
150741125
150763477
-
SLC25A6
chrX
1386152
1392113
-
STARD7
chr2
96184859
96208825
-
SUB1
chr5
32531633
32604079
+
TMSB4X
chrX
12975110
12977227
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.