Entry Detail


General Information

Database ID:exR0511014
RNA Name:ADPRHL2
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):36088892End Site(bp):36093932
External Links:ENSG00000116863



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RPS6KL1
chr14
74903951
74923302
-
VDAC2
chr10
75210154
75231448
+
MT-ND3
chrMT
10059
10404
+
ANAPC1
chr2
111611639
111884690
-
TESC
chr12
117038923
117099479
-
HCFC2
chr12
104064531
104106524
+
ATP5F1B
chr12
56638175
56645984
-
SRRT
chr7
100875103
100888664
+
CDK4
chr12
57747727
57756013
-
RAB14
chr9
121178133
121223014
-
OXSM
chr3
25782917
25794534
+
OAZ2
chr15
64687573
64703281
-
CA12
chr15
63321378
63381846
-
TTC28
chr22
27978014
28679865
-
MIGA1
chr1
77779624
77879539
+
CPZ
chr4
8592660
8619759
+
MCM5
chr22
35400134
35425431
+
BRWD1
chr21
39184176
39321559
-
IDI1
chr10
1039152
1049170
-
STX16
chr20
58651253
58679526
+
HLA-DQB1
chr6
32659467
32668383
-
TNFRSF1A
chr12
6328757
6342114
-
STRAP
chr12
15882387
15903478
+
HLA-B
chr6
31269491
31357188
-
SPCS1
chr3
52704955
52711148
+
TAGLN2
chr1
159918107
159925732
-
RNASEK
chr17
7012417
7014532
+
EID2
chr19
39538707
39540161
-
C1orf21
chr1
184387029
184629019
+
SLC7A5
chr16
87830023
87869507
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC144548.1
chr12
110387463
110445548
-
AL035458.2
chr20
34234840
34281173
-
LINC01641
chr1
227393554
227431035
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.