Entry Detail


General Information

Database ID:exR0511019
RNA Name:ADRA2C
RNA Type:mRNA
Chromosome:chr4
Starnd:+
Coordinate:
Start Site(bp):3766348End Site(bp):3768526
External Links:ENSG00000184160



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
AC093525.1
chr16
2513965
2527955
+
AGPS
chr2
177392757
177559299
+
ATP6V0C
chr16
2513952
2520218
+
BRCA1
chr17
43044295
43170245
-
EEF2
chr19
3976056
3985463
-
EIF1
chr17
41688885
41692668
+
EMID1
chr22
29205896
29259597
+
MAGED1
chrX
51803007
51902357
+
MARK2
chr11
63838928
63911019
+
MFGE8
chr15
88898683
88913381
-
NAP1L1
chr12
76036585
76084958
-
PCBP1
chr2
70087477
70089203
+
PKM
chr15
72199029
72231822
-
POLR3D
chr8
22245133
22254601
+
PRKD1
chr14
29576479
30191898
-
PSIP1
chr9
15464066
15510995
-
PTMA
chr2
231706895
231713541
+
RACK1
chr5
181236897
181248096
-
RPL8
chr8
144789765
144792587
-
SAMD11
chr1
923928
944581
+
SH3BP4
chr2
234952017
235055714
+
SNRPB
chr20
2461634
2470853
-
USO1
chr4
75724593
75814286
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC060780.1
chr17
43148368
43171037
-
FOXD3-AS1
chr1
63320884
63324441
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.