Entry Detail


General Information

Database ID:exR0511023
RNA Name:ADRM1
RNA Type:mRNA
Chromosome:chr20
Starnd:+
Coordinate:
Start Site(bp):62302093End Site(bp):62308862
External Links:ENSG00000130706



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
DDIT4
chr10
72273924
72276036
+
MIER2
chr19
301444
344815
-
TOPBP1
chr3
133598175
133662380
-
HLA-B
chr6
31269491
31357188
-
NPLOC4
chr17
81556887
81648465
-
P2RY11
chr19
10111693
10115372
+
TAGLN2
chr1
159918107
159925732
-
SREBF2
chr22
41833079
41907307
+
TUBA1B
chr12
49127782
49131397
-
DDX49
chr19
18919705
18929189
+
SELENOH
chr11
57741250
57743554
+
U2AF2
chr19
55654146
55674715
+
RPS9
chr19
54200809
54249003
+
MT-ND3
chrMT
10059
10404
+
PLEC
chr8
143915147
143976734
-
TEX261
chr2
70985942
70994873
-
OTUB1
chr11
63985853
64001811
+
GNAO1
chr16
56191489
56357444
+
GABARAP
chr17
7240008
7242449
-
VPS28
chr8
144423601
144428563
-
ENO1
chr1
8861000
8879190
-
TMEM8B
chr9
35814451
35865518
+
HSP90AB1
chr6
44246166
44253888
+
TMEM120B
chr12
121712752
121783001
+
NDUFV1
chr11
67605653
67612554
+
EMG1
chr12
6970913
6997428
+
MTREX
chr5
55307989
55425579
+
MT-CO3
chrMT
9207
9990
+
RGMB
chr5
98768650
98798643
+
ACAP3
chr1
1292390
1309609
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC139530.1
chr17
81701324
81703300
-
BX284668.2
chr1
16870945
16883659
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.