Entry Detail


General Information

Database ID:exR0511024
RNA Name:ADSL
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):40346500End Site(bp):40390463
External Links:ENSG00000239900



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MADD
chr11
47269161
47330031
+
HDGFL3
chr15
83112738
83207823
-
CLTC
chr17
59619689
59696956
+
MTRNR2L10
chrX
55181392
55182442
-
HNRNPR
chr1
23303771
23344336
-
TOMM7
chr7
22812628
22822852
-
MAPK6
chr15
51952106
52067375
+
STK11
chr19
1177558
1228431
+
SAP30
chr4
173369969
173377532
+
PPIAL4F
chr1
144592868
144593652
+
SND1
chr7
127652194
128092609
+
PPP1R18
chr6
30676389
30687895
-
BAG6
chr6
31639028
31652705
-
PSMD4
chr1
151254703
151267479
+
AHCY
chr20
34280268
34311802
-
AC104452.1
chr3
49416777
49429314
-
NICN1
chr3
49422946
49429326
-
ERG28
chr14
75649791
75660876
-
SGSM3
chr22
40370591
40410289
+
PFN2
chr3
149964904
150050788
-
RPS27A
chr2
55231903
55235853
+
TPM3
chr1
154155304
154194648
-
PHF19
chr9
120855651
120894896
-
ZNF20
chr19
12092843
12140355
-
PCCA
chr13
100089015
100530437
+
GIPC1
chr19
14477760
14496149
-
EEF1A1
chr6
73515750
73523797
-
DNAJA3
chr16
4425805
4456775
+
EZR
chr6
158765741
158819368
-
SLC25A17
chr22
40769630
40819399
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-193a-5p
chr17
31560016
31560037
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL031595.3
chr22
44139365
44153626
+
AL050341.2
chr1
40256427
40257967
-
AL139819.1
chr10
100335563
100346390
-
AL353759.1
chr6
26160765
26172802
-
MIR205HG
chr1
209428817
209432838
+
NFYC-AS1
chr1
40690380
40692066
-
SNHG25
chr17
64145970
64146476
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.