Entry Detail


General Information

Database ID:exR0511027
RNA Name:AEN
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):88621337End Site(bp):88632281
External Links:ENSG00000181026



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HSP90AA1
chr14
102080738
102139699
-
PTEN
chr10
87863625
87971930
+
MAPK9
chr5
180233143
180292099
-
PABPC1
chr8
100685816
100722809
-
ITM2C
chr2
230864639
230879248
+
KAT7
chr17
49788681
49835026
+
HCCS
chrX
11111301
11123086
+
MESD
chr15
80946289
80989828
-
PPP1CB
chr2
28751640
28802940
+
PEBP1
chr12
118136124
118145584
+
STARD7
chr2
96184859
96208825
-
YBX1
chr1
42682418
42703805
+
MYL6
chr12
56158161
56163496
+
STRN4
chr19
46719511
46746994
-
AC006538.2
chr19
2717769
2740048
-
APH1A
chr1
150265399
150269580
-
JUNB
chr19
12791486
12793315
+
TSR2
chrX
54440404
54448032
+
PLK1
chr16
23677656
23690367
+
MATK
chr19
3777970
3802129
-
CSDE1
chr1
114716913
114758676
-
FKBP8
chr19
18531751
18544077
-
TOR1A
chr9
129812942
129824244
-
R3HDM2
chr12
57253762
57431005
-
GBE1
chr3
81489703
81761645
-
IVD
chr15
40405485
40435947
+
GPBP1
chr5
57173948
57264679
+
ZNF202
chr11
123723914
123741675
-
HSPA4
chr5
133052013
133106449
+
MDK
chr11
46380756
46383837
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-24-3p
chr9
95086064
95086085
+
hsa-miR-27a-3p
chr19
13836447
13836467
-
hsa-miR-101-3p
chr1
65058442
65058462
-
hsa-miR-27b-3p
chr9
95085505
95085525
+
hsa-miR-513a-5p
chrX
147213538
147213555
-
hsa-miR-455-5p
chr9
114209449
114209470
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC007952.4
chr17
19112000
19112636
-
AC093827.4
chr4
86924630
86936202
-
AD000090.1
chr19
35557956
35581954
+
CCDC183-AS1
chr9
136803927
136808848
-
LNCPRESS1
chr7
101299578
101301346
+
NEAT1
chr11
65422774
65445540
+
SNHG3
chr1
28505980
28510892
+
XIST
chrX
73820649
73852723
-
ZFAS1
chr20
49278178
49299600
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.