Entry Detail


General Information

Database ID:exR0511028
RNA Name:AFAP1
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):7758714End Site(bp):7939926
External Links:ENSG00000196526



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RAPGEF1
chr9
131576770
131740074
-
PGAM1
chr10
97426191
97433444
+
RBX1
chr22
40951347
40973309
+
ZNF462
chr9
106863166
107013634
+
DKC1
chrX
154762742
154777689
+
PA2G4
chr12
56104537
56113910
+
NCL
chr2
231453531
231483641
-
LAMTOR2
chr1
156054782
156058506
+
GAPDH
chr12
6534512
6538374
+
EXOSC4
chr8
144078648
144080648
+
RPS14
chr5
150442635
150449739
-
WDR46
chr6
33279108
33289247
-
TCP1
chr6
159778498
159789703
-
PITX2
chr4
110617423
110642123
-
FNDC3A
chr13
48975912
49209779
+
PFN1
chr17
4945652
4949061
-
FKBP1A
chr20
1368978
1393172
-
HS6ST1
chr2
128236716
128318868
-
DTL
chr1
212035553
212107400
+
TNIK
chr3
171058414
171460408
-
GDAP1
chr8
74321130
74488872
+
ACOX3
chr4
8366282
8440723
-
YME1L1
chr10
27110112
27155266
-
ERP29
chr12
112013348
112023449
+
MT-CO1
chrMT
5904
7445
+
PABPC4
chr1
39560816
39576790
-
MT-ND2
chrMT
4470
5511
+
BOD1
chr5
173607145
173616659
-
NUCKS1
chr1
205712822
205750182
-
SPG7
chr16
89490719
89557768
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-193a-3p
chr17
31560050
31560071
+
hsa-miR-485-5p
chr14
101055427
101055448
+
hsa-miR-193b-3p
chr16
14304017
14304038
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-664b-5p
chrX
154768596
154768619
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AL355987.4
chr9
136799223
136810042
+
SNHG14
chr15
24978583
25420336
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.