Entry Detail


General Information

Database ID:exR0511035
RNA Name:AFG3L2
RNA Type:mRNA
Chromosome:chr18
Starnd:-
Coordinate:
Start Site(bp):12328944End Site(bp):12377227
External Links:ENSG00000141385



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RPS18
chr6
33272075
33276511
+
RPS23
chr5
82273320
82278396
-
SOX11
chr2
5692384
5701385
+
MT-CO2
chrMT
7586
8269
+
RPL3
chr22
39312882
39320389
-
N4BP2L2
chr13
32432417
32538885
-
CHMP5
chr9
33264879
33282070
+
PEAK1
chr15
77100656
77420144
-
PPP1CB
chr2
28751640
28802940
+
GDI2
chr10
5765223
5842132
-
PITX1
chr5
135027734
135034813
-
NUP107
chr12
68686951
68745809
+
DYNLL1
chr12
120469850
120498493
+
CAPN2
chr1
223701593
223776018
+
CSDE1
chr1
114716913
114758676
-
ALDOA
chr16
30064164
30070457
+
SLC41A1
chr1
205789094
205813748
-
TRAPPC1
chr17
7930345
7932123
-
ADH5
chr4
99070978
99088801
-
RPL35
chr9
124857880
124861981
-
LCP1
chr13
46125920
46211871
-
GAPDH
chr12
6534512
6538374
+
FLNA
chrX
154348524
154374638
-
BTG2
chr1
203305491
203309602
+
FASN
chr17
82078338
82098294
-
C17orf49
chr17
7014495
7017525
+
HK2
chr2
74834127
74893359
+
YBX1
chr1
42682418
42703805
+
THOC5
chr22
29505879
29555216
-
PTTG1IP
chr21
44849585
44873903
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC091564.7
chr11
6610883
6616594
-
AP001496.2
chr18
5232876
5238526
-
SNHG1
chr11
62851984
62855953
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.