Entry Detail


General Information

Database ID:exR0511037
RNA Name:AFMID
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):78187317End Site(bp):78207701
External Links:ENSG00000183077



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ALDOA
chr16
30064164
30070457
+
C8orf88
chr8
90958471
90985238
-
CCT7
chr2
73233420
73253021
+
CFL1
chr11
65823022
65862026
-
CNOT1
chr16
58519951
58629885
-
CRYBG2
chr1
26321698
26360080
-
CSRP2
chr12
76858709
76879023
-
EEF1D
chr8
143579697
143599541
-
FLNA
chrX
154348524
154374638
-
GTPBP3
chr19
17334920
17342731
+
HLA-DPB1
chr6
33075990
33089696
+
HOXD9
chr2
176122719
176124937
+
LMNB1
chr5
126776623
126837020
+
LPCAT1
chr5
1456480
1523962
-
MAP3K11
chr11
65597756
65615382
-
MYO1C
chr17
1464186
1492686
-
NCBP3
chr17
3802158
3846246
-
PCNP
chr3
101574180
101594465
+
PPIA
chr7
44796680
44824564
+
RANBP2
chr2
108719482
108785809
+
RBM5
chr3
50088919
50119021
+
SIPA1L1
chr14
71320449
71741229
+
SRA1
chr5
140537340
140558252
-
TLR7
chrX
12867072
12890361
+
UHRF1BP1
chr6
34792015
34883138
+
UQCRHL
chr1
15807169
15809348
-
USF2
chr19
35268962
35279821
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL021707.3
chr22
38734730
38738990
+
RMRP
chr9
35657751
35658018
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.