Entry Detail


General Information

Database ID:exR0511039
RNA Name:AFTPH
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):64524305End Site(bp):64593005
External Links:ENSG00000119844



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
BID
chr22
17734138
17774770
-
YWHAQ
chr2
9583967
9630997
-
CLEC2D
chr12
9664969
9699553
+
NAP1L1
chr12
76036585
76084958
-
DTYMK
chr2
241675747
241686944
-
TWSG1
chr18
9334767
9402420
+
TUBA1B
chr12
49127782
49131397
-
LAMC1
chr1
183023420
183145592
+
BIRC2
chr11
102347211
102378670
+
CUL3
chr2
224470150
224585397
-
PGK1
chrX
77910739
78129295
+
HLA-A
chr6
29941260
29945884
+
HEXA
chr15
72340919
72376476
-
STRN4
chr19
46719511
46746994
-
RPUSD4
chr11
126202096
126211692
-
HLA-F
chr6
29722775
29738528
+
BRPF3
chr6
36196744
36232790
+
CD48
chr1
160678746
160711831
-
ATP5MG
chr11
118401606
118431496
+
LCP1
chr13
46125920
46211871
-
ATP8B2
chr1
154325553
154351304
+
NCL
chr2
231453531
231483641
-
AKIRIN2
chr6
87674860
87702233
-
HNRNPU
chr1
244840638
244864560
-
HDAC2
chr6
113933028
114011308
-
PHF20
chr20
35771974
35950370
+
RPL32
chr3
12834485
12841582
-
MRPL4
chr19
10251901
10260055
+
RPL27
chr17
42998273
43002959
+
YWHAH
chr22
31944522
31957603
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
LINC01405
chr12
110934590
110959093
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.