Entry Detail


General Information

Database ID:exR0511040
RNA Name:AGA
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):177430774End Site(bp):177442437
External Links:ENSG00000038002



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ANAPC4
chr4
25377213
25418498
+
ATP6V1H
chr8
53715543
53843558
-
BTF3
chr5
73498408
73505635
+
CAPN1
chr11
65180566
65212006
+
CAT
chr11
34438934
34472060
+
CCDC169
chr13
36222008
36297840
-
CCDC169-SOHLH2
chr13
36168794
36297842
-
CHD8
chr14
21385194
21456126
-
FADS2
chr11
61792980
61867354
+
FAM107B
chr10
14518557
14774897
-
MCM2
chr3
127598410
127622436
+
MRPL3
chr3
131462212
131502983
-
MTRNR2L12
chr3
96617188
96618236
-
PFN1
chr17
4945652
4949061
-
PPM1A
chr14
60245752
60299087
+
PTGES3
chr12
56663341
56688408
-
PUM3
chr9
2720469
2844095
-
RPL13A
chr19
49487554
49492308
+
RPL27A
chr11
8682788
8714759
+
RPL5
chr1
92832013
92841924
+
RPL8
chr8
144789765
144792587
-
RPS20
chr8
56067295
56074581
-
SPNS1
chr16
28974221
28984548
+
SRGN
chr10
69088103
69104805
+
TAF7
chr5
141260225
141320784
-
TMBIM6
chr12
49707725
49764934
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC109460.3
chr16
28974804
28990775
+
LOH12CR2
chr12
12355406
12357067
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.