Entry Detail


General Information

Database ID:exR0511041
RNA Name:AGAP1
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):235494043End Site(bp):236131800
External Links:ENSG00000157985



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
KAT2A
chr17
42113111
42121367
-
LIN54
chr4
82909973
83012926
-
ENAH
chr1
225486835
225653142
-
OXSR1
chr3
38165089
38255484
+
NCOR2
chr12
124324415
124567589
-
LMAN2
chr5
177331567
177351668
-
NFATC2IP
chr16
28950807
28967097
+
C14orf132
chr14
96039324
96093889
+
HES6
chr2
238238267
238240662
-
SELENOW
chr19
47778585
47784686
+
HDAC3
chr5
141620876
141636849
-
CUL3
chr2
224470150
224585397
-
RPUSD1
chr16
784974
788397
-
SNX10
chr7
26291895
26374329
+
CNOT1
chr16
58519951
58629885
-
MEIS1
chr2
66433452
66573869
+
GIGYF2
chr2
232697299
232860575
+
TEX264
chr3
51662693
51704323
+
KIF1A
chr2
240713761
240821036
-
RPS27A
chr2
55231903
55235853
+
GNAS
chr20
58839718
58911192
+
TRAIP
chr3
49828601
49856574
-
GDAP2
chr1
117863485
117929621
-
DYNC1LI1
chr3
32525974
32570858
-
SLX1A
chr16
30193887
30197561
+
LRBA
chr4
150264435
151015727
-
GAPDH
chr12
6534512
6538374
+
PSMD7
chr16
74296814
74306288
+
SIPA1L2
chr1
232397965
232561558
-
HMGA2
chr12
65824131
65966295
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC022400.3
chr10
73674295
73730466
-
AGAP1-IT1
chr2
235505751
235507566
+
AGAP11
chr10
86970741
87010126
+
AL136982.1
chr10
86992406
87010203
+
NOP14-AS1
chr4
2934882
2961738
+
SLX1A-SULT1A3
chr16
30193892
30204310
+
TMEM147-AS1
chr19
35540738
35546029
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.