Entry Detail


General Information

Database ID:exR0511043
RNA Name:AGAP3
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):151085831End Site(bp):151144436
External Links:ENSG00000133612



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ZNF703
chr8
37695782
37700019
+
INTS1
chr7
1470277
1504389
-
AC010646.1
chr19
17235940
17255448
-
RNF11
chr1
51236273
51273447
+
SLC31A1
chr9
113221544
113264492
+
GFM1
chr3
158644278
158692575
+
NR2F6
chr19
17231883
17245940
-
DOCK1
chr10
126905409
127452517
+
TMEM181
chr6
158536436
158635428
+
TMEM241
chr18
23197144
23437961
-
CDC25A
chr3
48157146
48188417
-
POU5F1B
chr8
127322183
127420066
+
LONP1
chr19
5691834
5720572
-
KRT10
chr17
40818117
40822614
-
XYLT2
chr17
50346126
50363138
+
KDM4B
chr19
4969113
5153598
+
BSG
chr19
571277
583493
+
RPS6
chr9
19375715
19380236
-
PDGFA
chr7
497258
520296
-
FAM219B
chr15
74899992
74906883
-
HOXD11
chr2
176104216
176109754
+
ADA
chr20
44619522
44652233
-
HMGA1
chr6
34236873
34246231
+
CDK18
chr1
205504595
205532793
+
SLC25A39
chr17
44319625
44324870
-
ADIPOR1
chr1
202940826
202958572
-
MT-ND4L
chrMT
10470
10766
+
INA
chr10
103277138
103290346
+
WDR6
chr3
49007062
49015953
+
BUB3
chr10
123154402
123170467
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-299-5p
chr14
101023800
101023821
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC022400.3
chr10
73674295
73730466
-
AC087741.1
chr17
80200673
80205949
-
AC079949.1
chr12
127142029
127146532
-
AL355472.2
chr1
234357006
234365828
+
AL356488.2
chr1
109100193
109100619
+
FGD5-AS1
chr3
14920347
14948424
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.