Entry Detail


General Information

Database ID:exR0511044
RNA Name:AGAP6
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):49982190End Site(bp):50010499
External Links:ENSG00000204149



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AGAP1
chr2
235494043
236131800
+
AGAP3
chr7
151085831
151144436
+
AGAP4
chr10
45825594
45853875
-
AGAP5
chr10
73674285
73698159
-
AGAP9
chr10
47501854
47523638
-
ATXN1
chr6
16299112
16761491
-
BMPR2
chr2
202376327
202567751
+
MTRNR2L8
chr11
10507894
10509186
-
NACC1
chr19
13116862
13141147
+
RHOG
chr11
3826978
3840959
-
SMC1A
chrX
53374149
53422728
-
TIMM23B
chr10
49942049
49974850
+
TRRAP
chr7
98877933
99050831
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010451.1
chr5
4974690
5034267
-
AC022400.3
chr10
73674295
73730466
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.