Entry Detail


General Information

Database ID:exR0511048
RNA Name:AGBL5
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):27042364End Site(bp):27070622
External Links:ENSG00000084693



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CD151
chr11
832887
839831
+
WDR70
chr5
37379285
37753435
+
PCNA
chr20
5114953
5126626
-
MRPL20
chr1
1401909
1407293
-
EIF4B
chr12
53006158
53042209
+
CBS
chr21
43053191
43076943
-
SMC4
chr3
160399274
160434954
+
SCD
chr10
100347233
100364826
+
AMMECR1L
chr2
127861630
127885922
-
LIFR
chr5
38474668
38608354
-
XPO6
chr16
28097979
28211920
-
HNRNPA1
chr12
54280193
54287088
+
IGFBP2
chr2
216632828
216664436
+
TALDO1
chr11
747415
765012
+
SYVN1
chr11
65121780
65134533
-
RAB8A
chr19
16111889
16134234
+
FNBP1
chr9
129887187
130043194
-
POLR2E
chr19
1086574
1095380
-
SNX25
chr4
185204237
185370185
+
FAM76B
chr11
95768953
95790409
-
RPL4
chr15
66498015
66524532
-
CREBZF
chr11
85659708
85682908
-
SNU13
chr22
41673933
41690504
-
PSMB5
chr14
23016543
23035230
-
TOX4
chr14
21476597
21499175
+
RPL10
chrX
154389955
154409168
+
ENTPD4
chr8
23385783
23457695
-
URGCP-MRPS24
chr7
43866558
43906589
-
MRPS24
chr7
43866558
43869893
-
TIMM50
chr19
39480412
39493785
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC026362.1
chr12
122975320
122982907
+
AL139819.1
chr10
100335563
100346390
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.