Entry Detail


General Information

Database ID:exR0511050
RNA Name:AGFG1
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):227472152End Site(bp):227561214
External Links:ENSG00000173744



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MTRNR2L4
chr16
3370979
3372668
-
MRPS7
chr17
75261674
75266376
+
PCDH7
chr4
30720415
31146805
+
GNAS
chr20
58839718
58911192
+
COMMD1
chr2
61888724
62147247
+
FLOT2
chr17
28879335
28897733
-
UBE2W
chr8
73780097
73878910
-
C6orf47
chr6
31658298
31660778
-
TUBA1B
chr12
49127782
49131397
-
P2RX1
chr17
3896592
3916476
-
NDUFS7
chr19
1383527
1395589
+
BRD3
chr9
134030305
134068535
-
CCDC127
chr5
196868
218153
-
LAMP1
chr13
113297239
113323672
+
LSP1
chr11
1852970
1892267
+
RPSA
chr3
39406716
39412542
+
PIP4K2C
chr12
57591174
57603418
+
RACK1
chr5
181236897
181248096
-
EZH2
chr7
148807383
148884321
-
MEF2A
chr15
99565417
99716466
+
BSG
chr19
571277
583493
+
REXO1
chr19
1815248
1848483
-
ID1
chr20
31605283
31606515
+
MXD4
chr4
2247432
2262109
-
RPL27A
chr11
8682788
8714759
+
FEM1B
chr15
68277745
68295862
+
RPS23
chr5
82273320
82278396
-
AC116366.3
chr5
132410832
132646079
+
MRPL10
chr17
47823272
47831541
-
ATP5MPL
chr14
103912288
103928269
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-106b-5p
chr7
100094043
100094063
-
hsa-miR-380-3p
chr14
101025056
101025077
+
hsa-miR-1270
chr19
20399320
20399342
-
hsa-miR-4492
chr11
118910765
118910781
+
hsa-miR-5703
chr2
227472162
227472179
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
AP001330.4
chr8
101208148
101208558
+
GAS5
chr1
173858559
173868882
-
HOXA-AS2
chr7
27107777
27134302
+
NEAT1
chr11
65422774
65445540
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.