Entry Detail


General Information

Database ID:exR0511051
RNA Name:AGFG2
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):100539203End Site(bp):100568220
External Links:ENSG00000106351



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HK1
chr10
69269984
69401884
+
DUSP2
chr2
96143169
96145440
-
HMGA1
chr6
34236873
34246231
+
ADCY3
chr2
24819169
24919839
-
BLCAP
chr20
37492472
37527931
-
KCNQ5
chr6
72621792
73198851
+
LASP1
chr17
38869859
38921770
+
RPS5
chr19
58386400
58394806
+
CORO1B
chr11
67435510
67443821
-
RBM42
chr19
35629030
35637686
+
DDX5
chr17
64498254
64508199
-
RPS19
chr19
41860255
41872925
+
REEP5
chr5
112876385
112922289
-
HLA-A
chr6
29941260
29945884
+
VPS4A
chr16
69311350
69326939
+
SLC12A8
chr3
125082636
125212864
-
ZFP36L1
chr14
68787660
68796253
-
HLA-E
chr6
30489509
30494194
+
ARID3A
chr19
925781
975939
+
RPL13
chr16
89560657
89566828
+
PTPRCAP
chr11
67435510
67437682
-
SOX13
chr1
204073115
204127743
+
NMT1
chr17
45051610
45109016
+
CRKL
chr22
20917407
20953747
+
INAFM2
chr15
40323692
40326715
+
CDK1
chr10
60778331
60794852
+
TUBA1B
chr12
49127782
49131397
-
BASP1
chr5
17065598
17276843
+
TMEM54
chr1
32894594
32901438
-
TPT1
chr13
45333471
45341370
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009065.3
chr16
2091436
2095433
+
TMEM147-AS1
chr19
35540738
35546029
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.