Entry Detail


General Information

Database ID:exR0511053
RNA Name:AGK
RNA Type:mRNA
Chromosome:chr7
Starnd:+
Coordinate:
Start Site(bp):141551278End Site(bp):141655244
External Links:ENSG00000006530



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
EXOSC6
chr16
70246778
70251940
-
AL138752.2
chr9
37588413
38068687
-
TUBA1C
chr12
49188736
49274603
+
TOMM5
chr9
37582646
37592604
-
RTN3
chr11
63681446
63759891
+
LSS
chr21
46188141
46228824
-
SESN3
chr11
95165513
95232541
-
RPAP2
chr1
92299059
92402056
+
CBX5
chr12
54230942
54280133
-
TAF10
chr11
6606294
6612539
-
ID2
chr2
8678845
8684461
+
ZCCHC17
chr1
31296982
31364953
+
RBM5
chr3
50088919
50119021
+
ZNF426
chr19
9523223
9538645
-
ITGAL
chr16
30472719
30523185
+
KDM1A
chr1
23019443
23083689
+
ITGB5
chr3
124761948
124901418
-
ARIH2
chr3
48918821
48986382
+
PUF60
chr8
143816344
143829352
-
GALC
chr14
87837820
87993665
-
AL513165.2
chr9
37512547
37592469
-
PSMA2
chr7
42916861
42932185
-
LGR4
chr11
27365961
27472790
-
C5orf38
chr5
2752131
2755397
+
ABI1
chr10
26746593
26861087
-
AC010132.3
chr7
42909273
42932174
-
LSM4
chr19
18306230
18323274
-
FBXO21
chr12
117141988
117190531
-
MRPL15
chr8
54135241
54148514
+
HNRNPL
chr19
38836388
38852347
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC097634.1
chr3
71584943
71587409
+
GUSBP11
chr22
23638487
23717356
-
PURPL
chr5
27217714
27496994
+
SNHG1
chr11
62851984
62855953
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.