Entry Detail


General Information

Database ID:exR0511056
RNA Name:AGPAT1
RNA Type:mRNA
Chromosome:chr6
Starnd:-
Coordinate:
Start Site(bp):32168212End Site(bp):32178096
External Links:ENSG00000204310



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NAP1L3
chrX
93670930
93673578
-
UBC
chr12
124911604
124917368
-
ENO1
chr1
8861000
8879190
-
TRIM71
chr3
32817997
32897824
+
NEMP1
chr12
57055643
57088063
-
DBN1
chr5
177456608
177474401
-
DAG1
chr3
49468703
49535618
+
ABHD17C
chr15
80679684
80755621
+
ATR
chr3
142449007
142578733
-
MT-ND1
chrMT
3307
4262
+
SNRNP200
chr2
96274338
96321271
-
TMPO
chr12
98515512
98550379
+
DHFR
chr5
80626226
80654983
-
PAK6
chr15
40217428
40277487
+
NEK6
chr9
124257606
124353307
+
APP
chr21
25880550
26171128
-
GMPS
chr3
155870650
155944020
+
ACTG1
chr17
81509971
81523847
-
MFSD12
chr19
3538261
3574290
-
RPS3
chr11
75399515
75422280
+
RAI1
chr17
17681458
17811453
+
CBX1
chr17
48070052
48101478
-
SDHC
chr1
161314257
161375340
+
AL121753.1
chr20
35267885
35280043
-
EDC4
chr16
67873052
67884499
+
PTPN12
chr7
77537295
77640069
+
COX7A2L
chr2
42333546
42425088
-
RPL31
chr2
101002229
101024032
+
ELF1
chr13
40931924
41061440
-
SIX4
chr14
60709539
60724351
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC040162.3
chr16
67882461
67886367
+
GATA3-AS1
chr10
8050450
8053484
-
OIP5-AS1
chr15
41283990
41309737
+
SNHG16
chr17
76557764
76565348
+
XIST
chrX
73820649
73852723
-
ZNF436-AS1
chr1
23368997
23371839
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.