Entry Detail


General Information

Database ID:exR0511057
RNA Name:AGPAT2
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):136673143End Site(bp):136687457
External Links:ENSG00000169692



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABCA7
chr19
1039997
1065572
+
ARF1
chr1
228082660
228099212
+
CSNK1E
chr22
38290691
38318084
-
DNAJB6
chr7
157335381
157417439
+
ENO1
chr1
8861000
8879190
-
EP300
chr22
41092592
41180077
+
EZR
chr6
158765741
158819368
-
FTL
chr19
48965309
48966879
+
GEMIN5
chr5
154887411
154938211
-
ILF3
chr19
10654261
10692417
+
ITM2C
chr2
230864639
230879248
+
MTA1
chr14
105419820
105470729
+
MYD88
chr3
38138478
38143022
+
NELFE
chr6
31952087
31959038
-
NKX3-2
chr4
13540830
13544508
-
PLXNA3
chrX
154458281
154477779
+
POLD1
chr19
50384204
50418018
+
QPRT
chr16
29663279
29698699
+
RPL13A
chr19
49487554
49492308
+
RPS15
chr19
1438358
1440494
+
SRSF4
chr1
29147743
29181900
-
TNK2
chr3
195863364
195911945
-
TRAPPC12
chr2
3379675
3485094
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC019205.1
chr6
73263212
73301789
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.